Alcohols and polyols
- (1)
- (55)
- (343)
- (39)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (156)
- (1)
- (64)
- (27)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (6)
- (3)
- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (12)
- (145)
- (116)
- (7)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (9)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (2)
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- (2)
- (2)
- (1)
- (1)
- (3)
- (1)
- (3)
- (1)
- (5)
- (5)
- (2)
- (1)
- (2)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (7)
- (5)
- (1)
- (2)
- (5)
- (2)
- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
- (3)
- (2)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (27)
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (21)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
- (1)
- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (2)
- (2)
- (2)
- (9)
- (6)
- (8)
- (4)
- (1)
- (1)
- (1)
- (1)
- (2)
- (3)
- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (85)
- (1)
- (5)
- (72)
- (3)
- (5)
- (237)
- (4)
- (2)
- (2)
- (21)
- (279)
- (17)
- (1)
- (6)
- (278)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (733)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
- (3)
- (3)
- (4)
- (11)
- (3)
- (2)
- (1)
- (3)
- (2)
- (3)
- (2)
- (3)
- (1)
- (3)
- (6)
- (3)
- (2)
- (2)
- (2)
- (3)
- (7)
- (7)
- (1)
- (3)
- (2)
- (3)
- (3)
- (2)
- (1)
- (2)
- (3)
- (3)
- (1)
- (4)
- (3)
- (3)
- (6)
- (5)
- (6)
- (7)
- (3)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (2)
- (1)
- (2)
- (2)
- (1)
- (4)
- (3)
- (4)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (9)
- (2)
- (2)
- (2)
- (4)
- (1)
- (2)
- (1)
- (7)
- (2)
- (3)
- (2)
- (2)
- (6)
- (2)
- (4)
- (1)
- (11)
- (2)
- (2)
- (4)
- (6)
- (2)
- (4)
- (1)
- (1)
- (4)
- (8)
- (2)
- (3)
- (2)
- (13)
- (6)
- (2)
- (2)
- (14)
- (2)
- (3)
- (1)
- (2)
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- (1)
- (8)
- (2)
- (5)
- (2)
- (6)
- (2)
- (2)
- (1)
- (1)
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- (12)
- (2)
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- (2)
- (2)
- (3)
- (4)
- (9)
- (3)
- (6)
- (3)
- (5)
- (2)
- (7)
- (2)
- (3)
- (12)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (2)
- (11)
- (1)
- (3)
- (4)
- (1)
- (6)
- (4)
- (2)
- (4)
- (1)
- (2)
- (5)
- (2)
- (2)
- (6)
- (2)
- (2)
- (3)
- (2)
- (2)
- (7)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (2)
- (3)
- (3)
- (2)
- (2)
- (3)
- (5)
- (3)
- (2)
- (4)
- (4)
- (2)
- (2)
- (2)
- (3)
- (1)
- (7)
- (4)
- (5)
- (3)
- (6)
- (3)
- (2)
- (1)
- (4)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (3)
- (4)
- (2)
- (2)
- (2)
- (8)
- (1)
- (1)
- (2)
- (2)
- (3)
- (6)
- (2)
- (1)
- (3)
- (3)
- (3)
- (2)
- (2)
- (3)
- (2)
- (5)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (1)
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- (4)
- (2)
- (2)
- (3)
- (3)
- (2)
- (3)
- (6)
- (3)
- (2)
- (5)
- (2)
- (1)
- (4)
- (1)
- (12)
- (2)
- (10)
- (2)
- (1)
- (12)
- (3)
- (3)
- (1)
- (3)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (2)
- (7)
- (3)
- (4)
- (3)
- (1)
- (4)
- (2)
- (3)
- (2)
- (7)
- (4)
- (4)
- (3)
- (5)
- (2)
- (2)
- (2)
- (3)
- (2)
- (3)
- (2)
- (6)
- (1)
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- (1)
- (3)
- (6)
- (1)
- (4)
- (1)
- (3)
- (1)
- (2)
- (8)
- (2)
- (5)
- (4)
- (1)
- (2)
- (2)
- (1)
- (4)
- (8)
- (3)
- (5)
- (2)
- (6)
- (4)
- (2)
- (2)
- (5)
- (6)
- (2)
- (2)
- (3)
- (3)
- (3)
- (2)
- (5)
- (1)
- (2)
- (3)
- (4)
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- (1)
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Filtered Search Results
Medchemexpress LLC Noscapine (hydrochloride) | 912-60-7 | 99.9% | 449.88 | 250 MG
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Noscapine hydrochloride is an orally active phthalideisoquinoline alkaloid with potent antitussive effects. It activates sigma opioid receptors and inhibits Bradykinin non-competitively. It also disrupts microtubule dynamics, leading to mitotic arrest and apoptosis. This compound exhibits anticancer, neuroprotective, and anti-inflammatory activities, and can cross the blood-brain barrier.
- Activates sigma opioid receptors
- Non-competitive Bradykinin inhibitor
- Disrupts microtubule dynamics
- Induces mitotic arrest and apoptosis
- Exhibits anticancer activity
- Exhibits neuroprotective activity
- Exhibits anti-inflammatory activities
- Capable of crossing the blood-brain barrier
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC R-(+)-SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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R-(+)-SCH-23390 hydrochloride | 125941-87-9 | 99.8% | 324.24 | 25 MG
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC DC-BPi-11 hydrochloride | 97.0% | C20H24ClN5O2S | 1 ML
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DC-BPi-11 hydrochloride is an inhibitor of bromodomain PHD finger transcription factor (BPTF) with an IC50 of 698 nM. It significantly inhibits leukemia cell proliferation in human leukemia MV-4-11 cells (EC50 120 nM, IC50 0.89 μM). The compound decreases downstream oncogene expression and c-Myc protein levels, with minimal effects on normal cells. Intended for research use only.
- Inhibits bromodomain PHD finger transcription factor (BPTF)
- IC50 of 698 nM against BPTF
- Inhibits leukemia cell proliferation
- Decreases oncogene expression and c-Myc protein
- Minimal effects on normal cells
- Off-white to light yellow solid appearance
- Molecular weight: 433.95
- Chemical formula: C20H24ClN5O2S
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Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | 99.9% | 403.90 | 50 MG
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Bambuterol hydrochloride is a long-acting beta-adrenoceptor agonist (LABA) that is used to treat asthma; it is also a proagent of terbutaline.
- Acts as a long-acting beta-adrenoceptor agonist (LABA)
- Used in the treatment of asthma
- Functions as a proagent of terbutaline
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Medchemexpress LLC Carmoterol hydrochloride | 137888-11-0 | 98.7% | 404.89 g/mol | C21H25ClN2O4 | 10MM 1ML
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Carmoterol hydrochloride is a potent, selective, long-acting β2-adrenoceptor agonist supplied for research use. It is available as solid samples and as a ready-to-use 10 mM solution in DMSO (1 mL), and is intended for pharmacology and respiratory research including bronchodilation, asthma, and COPD models.
- High purity suitable for research use.
- Available as solid and as a 10 mM solution in DMSO.
- Molecular weight 404.89 g/mol.
- CAS number 137888-11-0 for unambiguous identification.
- Supplied as the hydrochloride salt for improved solubility.
- Suitable for β2-adrenergic receptor pharmacology studies.
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Medchemexpress LLC GW806742X (hydrochloride) | 98.3% | 610.01 | 10 MM * 1 ML
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GW806742X hydrochloride is an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor. It binds the MLKL pseudokinase domain with a Kd of 9.3 μM and has activity against VEGFR2 (IC50=2 nM). This compound retards MLKL membrane translocation and inhibits necroptosis. It is for research use only.
- ATP mimetic
- Potent MLKL inhibitor
- Binds MLKL pseudokinase domain
- Activity against VEGFR2
- Retards MLKL membrane translocation
- Inhibits necroptosis
- Inhibits necroptotic death of wild-type mouse dermal fibroblasts (MDFs) in a dose-dependent manner
- Shows inhibition of VEGF induced proliferation of HUVECs with an IC50 of 5 nM
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Medchemexpress LLC PF-562271 (hydrochloride) | 939791-41-0 | 98.10% | 543.95 | 5 MG
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PF-562271 hydrochloride is a potent, ATP-competitive, and reversible inhibitor targeting FAK (Focal Adhesion Kinase) and Pyk2 (Proline-rich tyrosine kinase 2) kinases, with IC50 values of 1.5 nM and 13 nM, respectively.
- Potent, ATP-competitive, and reversible kinase inhibitor.
- Selectively targets FAK and Pyk2 kinases.
- Exhibits IC50s of 1.5 nM for FAK and 13 nM for Pyk2.
- Also inhibits CDK2/E, CDK5/p35, CDK1/B, and CDK3/E.
- Impairs cell viability in various cell lines, including Ewing sarcoma.
- Inhibits FAK phosphorylation in vivo in a dose-dependent manner.
- Demonstrates positive effects on bone tumors, including decreased tumor growth and deposition of new bone.
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![Medchemexpress LLC Benzoic acid, 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro [5.5]undec-9-yl]methyl]phenoxy]-, hydrochloride (1:1) | 461023-63-2 | 99.9% | 614.17 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384286-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzoic acid, 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro [5.5]undec-9-yl]methyl]phenoxy]-, hydrochloride (1:1) | 461023-63-2 | 99.9% | 614.17 | 25 MG
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Aplaviroc hydrochloride is a CCR5 antagonist derived from SDP, with IC50s ranging from 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW. It is intended for research use only.
- Target: CCR5 antagonist
- Potency: Potent activity against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM
- Mechanism: Suppresses infectivity and replication of HIV-1MDR variants at low concentrations (IC50 values of 0.4 to 0.6 nM)
- Binding Affinity: Binds to CCR5 with high affinity (Kd value of 2.9±1.0 nM)
- Inhibition: Potently blocks rgp120/sCD4 binding to CCR5 with an IC50 value of 2.7 nM
- In Vivo Efficacy: Suppresses R5 HIV-1 viremia in hu-PBMC-NOG mice at a dosage of 60 mg/kg
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Medchemexpress LLC SGK1-IN-3 hydrochloride | 00-00-0 | 96.7% | 567.88 g/mol | C23H21Cl3N6O3S | 5 MG
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SGK1-IN-3 hydrochloride is the hydrochloride salt of a small-molecule inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1). It has reported potent activity (IC50 <1 μM) and is supplied as a solid research reagent for biochemical and cellular studies, including exploratory research in osteoarthritis.
- Potent SGK1 inhibition (IC50 <1 μM).
- Supplied as a solid suitable for biochemical and cellular assays.
- High reported purity for reliable experimental results.
- Available in small research pack sizes for screening and optimization.
- Useful for exploratory studies of SGK1-related pathways and disease models.
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Medchemexpress LLC Carmoterol hydrochloride | 137888-11-0 | 98.7% | 404.89 | C21H25ClN2O4 | 50MG
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Carmoterol hydrochloride is a long-acting, selective β2-adrenoceptor agonist supplied for laboratory research. It is provided as a solid for studies of bronchodilation in asthma and chronic obstructive pulmonary disease (COPD) models, with supplier-provided purity and storage data to support experimental planning.
- High purity suitable for research (98.7%).
- Solid, white to light yellow appearance.
- Available in multiple package sizes, including 50 MG.
- Store sealed at 4°C; in solvent store at -80°C (6 months) or -20°C (1 month).
- Useful for in vitro and in vivo respiratory pharmacology studies.
- For research use only; not for human or clinical use.
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Medchemexpress LLC mAChR-IN-1 (hydrochloride) | 119391-73-0 | 99.6% | 524.82 g/mol | C23H26ClIN2O2 | 10MM 1ML
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mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor antagonist (IC50 17 nM) provided for research use. It is offered as a solid and as a pre-made solution in DMSO, intended for in vitro pharmacology and receptor binding studies.
- Potent mAChR antagonist (IC50 17 nM).
- High purity: 99.6% (LCMS).
- Chemical formula: C23H26ClIN2O2.
- Molecular weight: 524.82 g/mol.
- Physical appearance: white to off-white solid.
- Available as solids (5-100 mg) and 10 mM solution in DMSO, 1 mL.
- Supplied for research use only.
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Medchemexpress LLC Aptiganel hydrochloride | 137160-11-3 | 99.9% | 339.86 | 10 MG
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Aptiganel hydrochloride (Cerestat) is a non-competitive NMDA receptor antagonist that demonstrates a neuroprotective effect.
- Non-competitive NMDA receptor antagonist
- Neuroprotective effect
- Purity: 99.89%
- Appearance: Solid
- Color: Off-white to light yellow
- Molecular weight: 339.86
- Formula: C20H22ClN3
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Medchemexpress LLC Indotecan hydrochloride | 1228035-68-4 | 99.8% | 514.95 | 5 MG
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Indotecan hydrochloride, an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor. It prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis.
- Potent Topoisomerase I inhibitor.
- Can be used for the research of visceral leishmaniasis.
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Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | MFCD03427293 | 99.9% | 403.90 | 100 MG
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Bambuterol hydrochloride, also known as (±)-Bambuterol hydrochloride, is a long-acting beta-adrenoceptor agonist (LABA). It is primarily utilized in the treatment of asthma and functions as a proagent of terbutaline. Intended for research use only, this product is contraindicated in pregnancy and for individuals with severely impaired liver function, requiring dose adjustments for renal impairment.
- Used in the treatment of asthma.
- Functions as a proagent of terbutaline.
- Intended for research use only.
- Purity of 99.9%.
- Available in solid form.
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Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | 403.90 | 5 MG
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Bambuterol hydrochloride is a long-acting beta-adrenoceptor agonist (LABA) and a prodrug of terbutaline, utilized in the treatment of asthma. It targets the Adrenergic Receptor and is involved in GPCR/G Protein and Neuronal Signaling pathways.
- Acts as a long-acting beta-adrenoceptor agonist (LABA)
- Targets the adrenergic receptor
- Functions as a prodrug of terbutaline
- Used in the treatment of asthma
- Storage conditions include 4°C sealed, away from moisture; in solvent, -80°C for 6 months or -20°C for 1 month
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